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Scientists, linking gene with serotonin and depression, offer insights to new treatments

For the more than 18 million Americans who suffer from depressive illnesses, the best pharmacological treatments are those that increase levels of serotonin, the brain chemical that regulates mood, sleep and memory. New research by an international team of scientists, led by Rockefeller Universit...
Science News

New 'PhyloGibbs' software helps scientists make sense of DNA

For scientists studying the link between genes and disease, there’s no shortage of information. The genomes of humans and many other animals have been sequenced and published for several years. The challenge is making sense of the data. A new algorithm designed by Eric Siggia’s Rockefeller labo...
Science News

New genetic sequencing technique reveals possible genetic protection from heroin addiction

Sometimes, when it comes to genetics, the smallest changes can make the biggest differences. New research from the laboratory of Mary Jeanne Kreek at Rockefeller University uses a novel sequencing approach to show that even very tiny differences within genes may help protect someone from heroin a...
Science News

Protein structure suggests bacteria may be more sophisticated than we thought

When a bacterium or virus infects a plant, the plant fights back: It kills off its own cells in the area that’s infected. This immune response, known as programmed cell death, kills the invading organisms, limits its spread in the plant, and results in characteristic brown patches on the plant’s...
Science News

Watching fruit fly larvae crawl towards odors provides clues to how smells are detected

In an effort to understand how smells influence behavior, Leslie Vosshall has been watching fly larvae inch their way across Petri dishes. It may not be high-tech, but this technique has been helping scientists study neurobiology for the past 20 years. And a refinement of it, in which the larvae’...
Science News

New evidence that SARS cripples the immune system

Researchers at the Aaron Diamond AIDS Research Center (ADARC) at Rockefeller University were deeply involved in AIDS research in China when the SARS epidemic broke out in 2003. With their extensive virology background and their knowledge of the country and its government, it was only natural that...
Science News

From cell to gel: refined protocol uses GFP to locate proteins and examine their interactions

There are two things cell biologists always want to know: where is their protein found and what other proteins does it associate with. A new protocol has been developed at the Rockefeller University that will enable scientists to answer both in one fell swoop. One of the most common ways scientis...
Awards and Honors

Paul Nurse elected trustee of HHMI

Rockefeller University President Paul Nurse has been elected a trustee of the Howard Hughes Medical Institute, a medical research organization dedicated to the discovery and dissemination of new knowledge in the life sciences. HHMI announced Nurse’s election on December 14. Nurse, 56, is one of 1...
Science News

Neurons in the brain change shape when stressed

Long-term stress, like the kind that occurs when someone cares for a chronically ill parent or spouse, can impair short-term memory. Researchers believe that this occurs because constant stress affects an area of the brain necessary for learning and memory, and the underlying mechanisms for this ...
Science News

Immune cell receptors act in combination to regulate attack

The complexities of the mammalian immune system allow our bodies to fend off countless diseases. But researchers are still working to pin down exactly how it works — and to understand why some people’s antibodies, and some therapeutic antibodies, are better able to fight off disease than others...
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