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Vaccine developed at Rockefeller University boosts natural killer T cells in patients with cancer

Both arms of immune system respond A new vaccine designed at The Rockefeller University boosted a type of fast-responding immune system cell called the natural killer T (NKT) cell in patients with advanced cancer. The study surprised researchers by revealing the ability of these NKT cells to spur...

Jeffrey Friedman, discoverer of leptin, receives Gairdner, Passano awards

Rockefeller University's Jeffrey M. Friedman, M.D., Ph.D., a molecular geneticist whose discovery of the hormone leptin and its role in regulating body weight has changed our understanding of the causes of human obesity, has received two prestigious awards for this work: the Gairdner Foundation I...

Rockefeller University researchers are changing the face of addiction treatment

New study shows that "contingency management" treatment increases patient success rates and improves the morale of clinic staff and administration People addicted to heroin, alcohol and other drugs of abuse often fail to stay clean because they won't go to or won't stay in treatment. Reporting in...

Mice with defective sperm offer clues to infertility in men

Findings may yield methods for improving fertility as well as developing male contraceptives For 40 percent of the estimated six million American couples battling infertility, the problem lies with the man. But help may be on the way. New research in mice by scientists at Rockefeller University a...

Renowned French neuroscientist Jean-Pierre Changeux receives Rockefeller University's science writing prize

Jean-Pierre Changeux, Ph.D., one of the boldest thinkers in modern neuroscience, received the Rockefeller University Lewis Thomas Prize for Writing about Science Tues., March 29. Paul Nurse, Ph.D., president of Rockefeller University, presented Changeux with the annual prize following a public le...

Researchers identify gene that plays major role in age-related blindness disease

By combining the tools of high-throughput biology and statistical genetics, scientists at Rockefeller University, Yale University School of Public Health and the National Eye Institute have identified a gene that confers susceptibility to age-related macular degeneration (AMD), the most common ca...

"Blinding" an insect's sense of smell may be the best repellent

"Pest insects have a profound negative impact on agriculture and human health," says Rockefeller University's Leslie Vosshall, Ph.D. "They are responsible for global losses of crops and stored agricultural products as well as the spread of many diseases." In the heated battle between people and i...

Despite causes of lupus proving complex, scientists get a new lead on potential treatment

Mouse studies yield cause and potential cure, with human studies in progress Scientists at The Rockefeller University have determined that despite the fact that the autoimmune disease lupus results from a combination of genetics that likely varies from person to person, a common “gatekeeper” ...

Rockefeller researchers identify new role for key protein that regulates separation of DNA in dividing cells

Rockefeller University scientists have revealed a new function of a key component of the mechanism that cells use to accurately separate chromosomes when they divide. Disruptions in this process can cause diseases such as cancer. Reporting in the January issue of Nature Cell Biology, Michael A. L...

Blocking alcohol's impact on brain cells

Rockefeller University scientists identify a protein that regulates alcohol-withdrawal seizures Seizures are the most life-threatening, as well as disconcerting, symptoms of withdrawal in people who are alcoholics and who abruptly stop drinking. Heavy consumption of alcohol, or ethanol, the subst...