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Rockefeller Researcher Roderick MacKinnon Receives 1999 Lasker Award

Rockefeller University Professor Roderick MacKinnon, M.D., has been named a recipient of the 1999 Albert Lasker Basic Medical Research Award, the nation's most distinguished honor for outstanding contributions to basic and clinical medical research. Roderick Mackinnon, M.D. MacKinnon, head of Roc...

No Viral Rebound After Stopping Drugs: An Anomalous Group of HIV Patients

Immune response boosted by prior interruptions in therapy An unusual group of HIV-infected patients who stopped taking antiviral drugs yet continued to suppress HIV replication may have somehow boosted their immune response against the virus by temporary therapy interruptions, researchers from th...

Rockefeller and Aaron Diamond Researchers Say Resistance to HIV Drugs May Be Higher Than Previously Thought

Scientists say widespread analysis of virus strains should guide AIDS therapy A study of patients infected with the AIDS virus revealed that about one in six was carrying a strain that is resistant to at least one of the drugs targeting HIV, researchers report from the Aaron Diamond AIDS Research...

Rockefeller Researchers Produce 3-D Picture of DNA-reading Molecular Machine

Researchers at The Rockefeller University have determined the first three-dimensional structure of the cellular RNA polymerase (RNAP), a molecular machine that activates individual genes by transcribing, or reading out, the instructions encoded in their DNA. The structure, published in the Sept. ...

Researchers Propose New Theory to Explain How Visual Pigments are "Tuned"

Scientists from the Howard Hughes Medical Institute (HHMI) at The Rockefeller University and from the University of California-Berkeley have proposed a new theory on how the human eye perceives colors. Using techniques of molecular biology and spectroscopy, the research, reported in the August is...

Rockefeller University Luncheon Honors Science Outreach Program, Promotes Siemens Westinghouse Competition

The Rockefeller University and the Siemens Foundation will sponsor a luncheon on Wednesday, August 18, to honor Rockefeller’s Science Outreach Program for high school students and teachers and to promote the Siemens Westinghouse Science and Technology Competition. Sponsored by The Siemens Founda...

Rockefeller Scientists Discover a Surprising New Cancer Gene

Scientists at The Rockefeller University have found, for the first time, that the persistent activation of a protein called Stat3 can, by itself, cause normal cells to behave like cancer cells. The research, reported in the August 6 issue of Cell, provides both a scientific surprise and a promisi...

Rockefeller Researchers Inject Cells, Boost Immune System in Humans

Findings take important first step toward vaccines for cancer, viruses A single injection of specialized immune system cells–removed from the bloodstream and exposed to a foreign substance–can trigger a potent immune response in humans that lasts for months, Rockefeller University researchers r...

Rockefeller and Michigan State Scientists Identify Dangers of Tamoxifen and Recommend Simple Corrective Measures

Researchers Urge Cautious Approach for Healthy Women Considering Tamoxifen A team of researchers at The Rockefeller University and Michigan State University has identified a biochemical mechanism that may cause the potentially life-threatening side-effects associated with use of the anti-breast c...

Rockefeller University Researchers Find Large Hole-Forming Protein in Bacteria -- A Potential Achilles' Heel?

Finding Opens Door on Dysentery, Bubonic Plague, Cholera and Salmonella Poisoning Researchers at The Rockefeller University have shown for the first time that a protein called pIV forms a hole in the outer membrane of the bacterium E. coli to allow passage of large molecules. The finding, reporte...