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In the News - Scientific American - Greengard turns 90

A Nobel Laureate Turning 90 Continues to Churn Out Ideas for New Drugs   "Paul Greengard has been busy. In August he co-authored a paper on molecules that appear to regulate genes that might protect against Parkinson’s. That same month he took the lead on another paper that describes a protei...
Science News

Researchers discover new aspect of gene regulation and a possible target for cancer drugs

There are about 20,000 genes in the human genome, but not all are used in all cells at all times. At any given moment, a cell is converting only roughly half its genes into proteins. And of those active genes, about 75 percent are regulated by a process known as “RNA polymerase pausing.” This...
Science News

Study suggests new way to help the immune system fight off sleeping sickness parasite

Some infectious diseases are particularly difficult to treat because of their ability to evade the immune system. One such illness, African sleeping sickness, is caused by the parasite Trypanosoma brucei, transmitted by the tsetse fly, and is fatal if left untreated. The trypanosome parasite is t...
Campus News

Helen Hobbs receives Rockefeller’s Pearl Meister Greengard Prize

by Katherine Fenz, media relations manager Helen Hobbs, a cardiology researcher, received the 2015 Pearl Meister Greengard Prize during a festive event in the Caspary Auditorium last month. The award, which Dr. Hobbs received for her pioneering research into the genetics of high cholesterol and ...
Science News

New research helps to explain how temperature shifts the circadian clock

For many living things, a roughly 24-hour internal clock governs the rhythms of life—everything from sleep in animals, to leaf opening in plants and reproduction in bread mold. Scientists have come to understand much about this internal time-keeping system, but one important aspect, its complex r...
Science News

Study reveals new mechanism in nicotine addiction

Part of the reason people find smoking difficult to quit is that each time they have a cigarette, feelings of craving, irritability and anxiety melt away. This component of addiction is known as negative reward and is controlled in part by a region of the brain called the habenula. The neurotrans...

In the News - STAT - McEwen

There's no such thing as a male or female brain, study finds   "These results add to a complex picture that you’d never guess from media accounts and pop psych books. After decades of research, 'we’re still debating the question of whether there are sex differences in the [human] brain and ...
Science News

A newly discovered signaling molecule helps neurons find their way in the developing brain

During embryonic development, billions of neurons nimbly reposition themselves within the brain and spinal cord, and connect branches to form the neural circuits that ultimately control our movements, perception, and memory. Scientists have long sought to understand the driving forces in this met...

In the News - The Lancet - Dubos

Antibiotic antagonist: the curious career of René Dubos   "Fortunately, Lederberg had been paying attention and in the late 1980s he used his position as head of the Rockefeller University to revive Dubos's warnings about the mutability and adaptability of pathogens in the face of shifting diseas...
Science News

Mutations in key cancer protein suggest new route to treatments

For years, scientists have struggled to find a way to block a protein known to play an important role in many cancers. The protein, STAT3, acts as a transcription factor—it performs the crucial task of helping convert DNA into the RNA instructions used to make new proteins. But when overly acti...
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