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Rockefeller University Researchers Find Large Hole-Forming Protein in Bacteria -- A Potential Achilles' Heel?

Finding Opens Door on Dysentery, Bubonic Plague, Cholera and Salmonella Poisoning Researchers at The Rockefeller University have shown for the first time that a protein called pIV forms a hole in the outer membrane of the bacterium E. coli to allow passage of large molecules. The finding, reporte...

Rockefeller University Scientists Receive Prestigious Awards for Cancer Research

General Motors Recognizes World's Foremost Cancer Scientists DETROIT — Arnold J. Levine, Ph.D., newly appointed president of The Rockefeller University, and Robert G. Roeder, Ph.D., professor and head of the Laboratory of Biochemistry and Molecular Biology, have been recognized by the General Mot...

Neurobiologists Show How the Brain Processes Signals from Pheromones

Researchers at The Rockefeller University have shown for the first time in mice how the brain processes signals from pheromones, essential chemicals used by animals to communicate with each other. Reported in the April 16 issue of Cell, the findings provide the first look at the "wiring diagram" ...

Researchers Shed Light on How Cells Commit Suicide

A team of researchers led by Associate Professor David Cowburn, Ph.D., has determined the three-dimensional structure of a molecule that regulates programmed cell death, a critical process important for many diseases, including cancer, heart disease and autoimmunity. The structure, reported in th...

Researchers Report Emergence of Antibiotic Resistance during Vancomycin Therapy

Antibiotic Combination Shown To Be Effective against Resistant Bug A team of researchers led by The Rockefeller University's Alexander Tomasz, Ph.D., have described the case of a 79-year-old patient whose death in a New York metropolitan area hospital last March was associated with a bloodstream ...

A Little Stress May Have Big Benefits for Health

Rockefeller University Researchers Show That Acute Stress Sends Early Warning Signal to Immune System Rockefeller University researchers have shown that brain hormones rally immune cells in response to stress. The findings, reported in the Feb. 2 issue of the Proceedings of the National Academy o...

400 High School Students Attack Foreign Invaders!: RU Mirsky Lecture on the Body's Immune Response

When a foreign invader such as a harmful bacterium, virus, fungus or parasite assaults the body, the immune system comes to the rescue by launching a cellular attack. Yet, some substances, such as cancerous growths, can elude the body's intricate detection system. Why? On Monday, December 28, fro...

Rockefeller Discoveries Named Breakthroughs of the Year by Science Magazine

The Rockefeller University, the nation's first biomedical research institute, will celebrate its Centennial in just two years. Most of the greatest scientific discoveries of the century are rooted in Rockefeller, including two Science magazine breakthroughs of 1998-on circadian rhythm and the bio...

Scientists Show That Normal-looking Cells in Cervical Cancer May Be Abnormal

Findings may broaden definition of cancer, leading to improved diagnostics and treatments Researchers from The Rockefeller University and Digilab, using a technique called infrared (IR) spectroscopy, have shown that normal-looking cells taken from women with cervical cancer may actually be abnorm...

Scientists Show for the First Time How Leprosy Bug Targets Peripheral Nerves

A team of researchers, led by scientists from The Rockefeller University, have identified how the bacterium that causes leprosy targets the peripheral nerve, the crucial step leading to nerve damage in this disease. The findings, reported in the Dec. 11 issue of the journal Science, open a window...