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Proceedings of the National Academy of Sciences USA online: August 26, 2013

Proceedings of the National Academy of Sciences USA online: August 26, 2013 H3R42me2a is a histone modification with positive transcriptional effects Fabio Casadio, Xiangdong Lu,  Samuel B. Pollock, Gary LeRoy, Benjamin A. Garcia, Tom W. Muir, Robert G. Roeder and C. David  Allis

Journal of Experimental Medicine 210: 1,871-1,888 (8-26-13)

Journal of Experimental Medicine 210: 1,871-1,888 Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract Darren Ruane, Lucas Brane, Bernardo Sgarbi Reis, Cheolho Cheong, Jordan Poles, Yoonkyung Do, Hongfa Zhu, Klara Velinzon, Jae-Hoon Choi, Natalie Studt, Lloyd ...

Immunity 39: 245-258 (8-22-13)

Immunity 39: 245-258 Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies Tongqing Zhou, Jiang Zhu, Xueling Wu, Stephanie Moquin, Baoshan Zhang, Priyamvada Acharya, Ivelin S. Georgiev, Han R. Altae-Tran, G...

Cell online: August 20, 2013

Cell online: August 20, 2013 Serotonin and the neuropeptide PDF initiate and extend opposing behavioral states in C. elegans Steven W. Flavell, Navin Pokala, Evan Z. Macosko, Dirk R. Albrecht, Johannes Larsch and Cornelia I. Bargmann

Cell 154: 748-762 (8-15-13)

Cell 154: 748-762 Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA Pu Gao, Manuel Ascano, Thomas Zillinger, Weiyi Wang, Peihong Dai, Artem A. Serganov, Barbara L. Gaffney, Stewart  Shuman, Roger A. Jones, Liang Deng, Gunther Hartmann, Winfr...
Science News

New technique in RNA interference cuts time and cost in genetic screens

There is a new contender in the field of gene discovery, and it’s giving knockout mice a run for their money. Researchers at The Rockefeller University have shown that a new technique using RNA interference is able to find genes that cause epidermal tumor growth in months rather than the decades ...
Campus News

Structural biologist, interested in ribosome assembly, to join Rockefeller faculty

At the heart of the central dogma of biology — that DNA makes RNA and RNA makes proteins — is the ribosome. Ribosomes serve as a cell’s protein factories, linking amino acids together into complex proteins according to instructions encoded in the cell’s messenger RNAs. It’s a process that ...

Nature online: August 14, 2013

Nature online: August 14, 2013 RNAi screens in mice identify physiological regulators of oncogenic growth Slobodan Beronja, Peter Janki, Evan Heller, Wen-Hui Lien, Brice E. Keyes, Naoki Oshimori and Elaine Fuchs

Proceedings of the National Academy of Sciences USA online: August 8, 2013

Proceedings of the National Academy of Sciences USA online: August 8, 2013 UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling Carlene Moore, Ferda Cevikbas, H. Amalia Pasolli, Yong Chen, Wei Kong, Cordula Kempkes,...
Science News

Researchers find molecule that causes sunburn pain

The painful, red skin that comes from too much time in the sun is caused by a molecule abundant in the skin’s epidermis, a new study published in the Proceedings of the National Academy of Sciences shows. Blocking the molecule, called TRPV4, greatly protects against the painful effects of sunburn...
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