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Variations in key genes increases Caucasians' risk of heroin addiction

Sometimes, small changes do add up. In the case of addictive diseases, tiny variations in a few genes can increase or decrease the likelihood of some people developing a dependency on heroin. Now, by examining a select group of genetic variants in more than 400 former severe heroin addicts, Rocke...

A blood marker may indicate Alzheimer's risk

A simple blood test capable of predicting if a person might develop Alzheimer’s disease is within sight, and could eventually be used to help scientists reverse onset of the disease in those most at risk. According to new research by Rockefeller University scientists and their colleagues at Colum...

New Rockefeller faculty member studies cancer metastasis

Sohail Tavazoie, a physician-scientist whose research focuses on the molecular basis of cancer metastasis, has been named assistant professor and will join The Rockefeller University as head of the Laboratory of Systems Cancer Biology in January 2009. Tavazoie, who received his Ph.D. from Harvard...

Abuse of painkillers can predispose adolescents to lifelong addiction

No child aspires to a lifetime of addiction. But their brains might. In new research to appear online in the journal Neuropsychopharmacology today, Rockefeller University researchers reveal that adolescent brains exposed to the painkiller OxyContin can sustain lifelong and permanent changes in th...

C. Erec Stebbins awarded prestigious EUREKA grant

C. Erec Stebbins, associate professor at The Rockefeller University, has been awarded an inaugural EUREKA grant from the National Institutes of Health for a project aimed at exploiting a bacteria-based “nanosyringe” as a means of delivering proteins into specific cells for therapeutic purposes. ...

Clinical study to examine role of vitamin D in kidney disease

Vitamin D is the key to preventing rickets and osteoporosis, but Rockefeller University scientists suspect it may also play a role in heading off atherosclerosis in people with chronic kidney disease. In a new clinical study, investigators at The Rockefeller University Hospital are examining pati...

Newly uncovered cells may be critical in psoriasis

Psoriasis, one of humanity’s oldest known diseases, has also been one of its most misunderstood. But in a new study that could change researchers’ perspective of the skin disorder and potentially lead to powerful new drug targets, Rockefeller University scientists have found that the source of p...

Rifamycin antibiotics attack tuberculosis bacteria with walls, not signals

Amid concerns about the rising number of new tuberculosis cases worldwide, researchers at Rockefeller University and their collaborators have reexamined and disproved a theory that describes how a potent class of antibiotics kills a deadly form of bacteria. The findings, which will appear in this...

Intensity of human environmental impact may lessen as incomes rise, analysis suggests

The richer you are, the more of the world’s resources you can afford to consume. But in many parts of the world, rising incomes are not having the proportionate effect on energy consumption, croplands and deforestation that one might expect, a new 25-year study shows. By examining a variety of go...

By amplifying cell death signals, scientists make precancerous cells self-destruct

When a cell begins to multiply in a dangerously abnormal way, a series of death signals triggers it to self-destruct before it turns cancerous. Now, in research to appear in the August 15 issue of Genes & Development, Rockefeller University scientists have figured out a way in mice to amplify the...