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Unique mutation reveals a new role for well-known DNA-repair gene

The discovery of a rare mutation in BRCA2, commonly known as the breast cancer gene, has shed new light on how cells safeguard their genetic material.
 

Study reveals first evidence inherited genetics can drive cancer’s spread

Scientists have long struggled to understand what drives a tumor to seed itself elsewhere in the body. New research implicates our own pre-existing genetics.

Rockefeller scientists investigate life-threatening inflammation affecting children with COVID-19

The condition resembles a rare childhood illness, Kawasaki disease. Researchers are analyzing blood samples to find genetic clues to what might be causing it.

Mice with patchy coats lay bare how stem cells endure

Scientists have discovered how stem cells in the skin maintain their ability to replenish themselves, a process critical for hair growth. The findings suggest that errors in stem cell maintenance might contribute to permanent hair-loss conditions.

The gene hunt to explain why some young, healthy people die from COVID-19

People under 50 without preexisting conditions typically develop mild symptoms of coronavirus infection—but there are exceptions. Researchers are working to identify rare genetic variations that may explain why some in this group have succumbed to the disease.

Scientists are using ‘elite’ antibodies from COVID-19 survivors to develop potent therapies

Most people infected with the coronavirus are able to fight it off because their immune system produces effective antibodies. Rockefeller scientists are working to turn such antibodies into a drug.


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Study captures the molecular architect of cells’ infrastructure

Using atomic-resolution technology, scientists have constructed the most detailed view yet of the molecular complex that decides where microtubules form.

New faculty member designs chemical probes to dissect and alter immune protein function

Ekaterina Vinogradova, an organic chemist, investigates the functions of immune proteins, with the goal of finding new targets for therapies. She will join Rockefeller as an assistant professor on January 1, 2021.

Researcher studying the dynamics of gene activity, cell by cell, joins Rockefeller faculty

Junyue Cao examines patterns of gene expression in order to better understand how cells differentiate into distinct types and how the body’s organs maintain stable populations of cells throughout life. He will move to Rockefeller as an assistant professor this summer.

Stavros Niarchos Foundation donates $3 million to Rockefeller COVID-19 research

The grant bolsters Rockefeller’s round-the-clock research initiatives related to COVID-19 and the SARS-CoV-2 virus that causes it.