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"Crucial evolutionary link": Molecular sculptor may have molded simple ancient bacterial cells into modern, highly structured cells

A team of researchers led by Rockefeller University's Michael P. Rout, Ph.D., have discovered a possible crucial evolutionary link between the simple cells that make up bacteria and the more complex cells that comprise animal and plant cells, including those of humans. This molecular sculptor may...
Science News

Cellular Two Step

Time-lapse movies show brain cells move like a two-stroke engine Following the often-quoted advice of Yogi Berra — "You can observe a lot by just watching" — Rockefeller University scientists show that nerve cells in the developing brains of humans and other mammals move in a two-part "step" le...
Science News

DNA barcodes find four new bird species

Short stretch of DNA sequence fast, accurate method for identifying species The task of identifying Earth's estimated 10 million species has daunted biologists for centuries - fewer than two million have been named. Using a technique called DNA barcoding, researchers at Rockefeller University and...
Science News

Essential smell gene may prove key to new insect repellents

Repellents that block gene might help fight malaria and other infectious diseases Insects navigate by smell to find food, mates and — in the case of disease-spreading mosquitoes — humans to bite. Researchers at Rockefeller University report in the September 2 issue of Neuron that insect...
Science News

Silencing human gene through new science of epigenetics; Gene associated with human development—and cancer

For the first time, scientists have shown how the activity of a gene associated with normal human development, as well as the occurrence of cancer and several other diseases, is repressed epigenetically — by modifying not the DNA code of a gene, but instead the spool-like histone proteins around...
Science News

Single isolated mouse skin cell can generate into variety of epidermal tissues

Sheets of stem cells, created in the lab, grow hair, skin and oil glands on hairless mice Researchers at the Howard Hughes Medical Institute at The Rockefeller University have isolated stem cells from the skin of a mouse, and showed, for the first time, that an individual stem cell can renew itse...
Science News

"Genome destroyer" identified in the immune system

Enzyme called AID is the initial culprit in B cell cancers Our bodies have such great capacity to heal, it's hard to imagine that we naturally manufacture a product in our immune system that can endanger our own DNA and provide a biological footstep to cancer. But this is precisely the case. In t...
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Hormone replacement therapy one hour at a time

Rodent study suggests approach to keep good and lose bad effects of standard hormone treatments Giving hormone doses in pulses, rather than as a steady exposure, may maximize the benefits and limit the side effects now associated with hormone therapies. This is one implication of the findings sci...
Science News

Viral locksmith is caught in the act

Interactions between viral and bacterial proteins promise new directions for antibiotics How does the molecular machine responsible for activating genes choose which gene to switch on, from among the 30,000 genes contained in each cell of the human body? In the August 4 issue of the EMBO Journa...
Campus News

Rockefeller University establishes stem cell research center

                $5 million endowment by NYC philanthropist Harriet Heilbrunn for research to advance basic research knowledge about stem cells   For more information about Rockefeller research using stem cells, visit http://www.rockefeller.edu/stemcell.   With the support of...
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