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A Google Map of Our Brains: The Next Chapter in Neuroscience   "For a lot of the way that different brain regions work together to generate complex functions, we're really stumbling around in the dark," said Dr. Cori Bargmann, a Rockefeller University neuroscientist and co-chair of the project. "...

Nature Structural and Molecular Biology online: September 1, 2013

Nature Structural and Molecular Biology online: September 1, 2013 Regulation of transcription by the MLL2 complex and MLL complex–associated AKAP95 Hao Jiang, Xiangdong Lu, Miho Shimada, Yali Dou, Zhanyun Tang and Robert G. Roeder

Proceedings of the National Academy of Sciences USA online: August 26, 2013

Proceedings of the National Academy of Sciences USA online: August 26, 2013 H3R42me2a is a histone modification with positive transcriptional effects Fabio Casadio, Xiangdong Lu,  Samuel B. Pollock, Gary LeRoy, Benjamin A. Garcia, Tom W. Muir, Robert G. Roeder and C. David  Allis

Proceedings of the National Academy of Sciences USA online: August 26, 2013

Proceedings of the National Academy of Sciences USA online: August 26, 2013 H3R42me2a is a histone modification with positive transcriptional effects Fabio Casadio, Xiangdong Lu,  Samuel B. Pollock, Gary LeRoy, Benjamin A. Garcia, Tom W. Muir, Robert G. Roeder and C. David  Allis

Journal of Experimental Medicine 210: 1,871-1,888 (8-26-13)

Journal of Experimental Medicine 210: 1,871-1,888 Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract Darren Ruane, Lucas Brane, Bernardo Sgarbi Reis, Cheolho Cheong, Jordan Poles, Yoonkyung Do, Hongfa Zhu, Klara Velinzon, Jae-Hoon Choi, Natalie Studt, Lloyd ...

Immunity 39: 245-258 (8-22-13)

Immunity 39: 245-258 Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies Tongqing Zhou, Jiang Zhu, Xueling Wu, Stephanie Moquin, Baoshan Zhang, Priyamvada Acharya, Ivelin S. Georgiev, Han R. Altae-Tran, G...

Cell online: August 20, 2013

Cell online: August 20, 2013 Serotonin and the neuropeptide PDF initiate and extend opposing behavioral states in C. elegans Steven W. Flavell, Navin Pokala, Evan Z. Macosko, Dirk R. Albrecht, Johannes Larsch and Cornelia I. Bargmann

Cell 154: 748-762 (8-15-13)

Cell 154: 748-762 Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA Pu Gao, Manuel Ascano, Thomas Zillinger, Weiyi Wang, Peihong Dai, Artem A. Serganov, Barbara L. Gaffney, Stewart  Shuman, Roger A. Jones, Liang Deng, Gunther Hartmann, Winfr...

New technique in RNA interference cuts time and cost in genetic screens

There is a new contender in the field of gene discovery, and it’s giving knockout mice a run for their money. Researchers at The Rockefeller University have shown that a new technique using RNA interference is able to find genes that cause epidermal tumor growth in months rather than the decades ...

Structural biologist, interested in ribosome assembly, to join Rockefeller faculty

At the heart of the central dogma of biology — that DNA makes RNA and RNA makes proteins — is the ribosome. Ribosomes serve as a cell’s protein factories, linking amino acids together into complex proteins according to instructions encoded in the cell’s messenger RNAs. It’s a process that ...