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Cell 151: 1005-1016 (11-21-12)

Cell 151: 1005-1016 Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein Joseph Osmundson, Cristina Montero-Diez, Lars F. Westblade, Ann Hochschild and Seth A. Darst

Neuron 76: 735-749 (11-21-12)

Neuron 76: 735-749 14-3-3 proteins regulate a cell-intrinsic switch from sonic hedgehog-mediated commissural axon attraction to repulsion after midline crossing Patricia T. Yam, Christopher B. Kent, Steves Morin, W. Todd Farmer, Ricardo Alchini, Léa Lepelletier, David R. Colman, Marc Tessier-Lavi...

Cell 151: 1068-1082 (11-21-12)

Cell 151: 1068-1082 Convergent multi-miRNA targeting of ApoE drives LRP1/LRP8-dependent melanoma metastasis and angiogenesis Nora Pencheva, Hien Tran, Colin Buss, Doowon Huh, Marija Drobnjak, Klaus  Busam and Sohail F. Tavazoie

Proceedings of the National Academy of Sciences USA 109: E3268-3277 (11-20-12)

Proceedings of the National Academy of Sciences USA 109: E3268-3277 Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies Hugo Mouquet, Louise Scharf, Zelda Euler, Yan Liu, Caroline Eden, Johannes F.  Scheid, Ariel Halper-Stromberg, Priyanthi N. P. Gnanapragasam, Daniel ...

Proceedings of the National Academy of Sciences USA 109: 19274-19279 (11-20-12)

Proceedings of the National Academy of Sciences USA 109: 19274-19279 Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel Manuel D. Leonetti, Peng Yuan, Yichun Hsiung and Roderick MacKinnon
Science News

Brain displays an intrinsic mechanism for fighting infection

White blood cells have long reigned as the heroes of the immune system. When an infection strikes, the cells, produced in bone marrow, race through the blood to fight off the pathogen. But new research is emerging that individual organs can also play a role in immune system defense, essentially b...

Molecular Cell online: November 8, 2012

Molecular Cell online: November 8, 2012 Transcriptome-wide miR-155 binding map reveals widespread noncanonical microRNA targeting Gabriel B. Loeb, Aly A. Khan, David Canner, Joseph B. Hiatt, Jay Shendure, Robert B. Darnell, Christina S. Leslie and Alexander Y. Rudensky
Science News

Potent antibodies neutralize HIV and could offer new therapy, study finds

Having HIV/AIDS is no longer a death sentence, but it’s still a lifelong illness that requires an expensive daily cocktail of drugs — and it means tolerating those drugs’ side effects and running the risk of resistance. Researchers at The Rockefeller University may have found something better:...

Nature Immunology online: October 28, 2012

Nature Immunology online: October 28, 2012 Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency Bertrand Boisson, Emmanuel Laplantine, Carolina Prando, Silvia Giliani, Elisabeth  Israelsson, Zhaohui Xu, Avinash Abhyankar, Laura Israël, Girald...

Nature online: October 28, 2012

Nature online: October 28, 2012 Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells Fabien G. Lafaille, Itai M. Pessach, Shen-Ying Zhang, Michael J. Ciancanelli, Melina Herman, Avinash Abhyankar, Shui-Wang Ying, Sotirios Keros, Peter A.  Goldstein, Gustavo Mostosla...
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