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In the News

Growing Pains: Nations Balance Growth, Power Needs   "These days electricity is so important to industrial society that providing adequate power isn't good enough. For example, businesses that rely on the Internet simply can't afford to be without power, even for a minute. Sure, it was a nuisance...

The Journal of Experimental Medicine online: August 7, 2012

The Journal of Experimental Medicine online: August 7, 2012 Heterozygous TBK1 mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood Melina Herman, Michael Ciancanelli, Yi-Hung Ou, Lazaro Lorenzo, Maja Klaudel-Dreszler, Elodie Pauwels, Vanessa Sancho-Shimizu, Rebeca ...

In the News

Technology: Problem or Solution?   "On the other hand, ask [Jesse Ausubel] about climate change (a subject he helped make the hot topic it is today), or overpopulation, or deforestation and you’ll get a surprisingly reassuring answer: things are getting better, we’re on the right track. It’s...

Cell 150: 533-548 (August 3, 2012)

Cell 150: 533-548 (August 3, 2012) Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling Moumita Chaki, Rannar Airik, Amiya K. Ghosh, Rachel H. Giles, Rui Chen, Gisela G. Slaats, Hui Wang, Toby W. Hurd, Weibin Zhou, Andrew Cluckey, Heon Yun...

Science online: August 2, 2012

Science online: August 2, 2012 Mycobacterial Disease and Impaired IFN-γ Immunity in Humans with Inherited ISG15 Deficiency Dusan Bogunovic, Minji Byun, Larissa A. Durfee, Avinash Abhyankar, Ozden Sanal, Davood Mansouri, Sandra Salem, Irena Radovanovic, Audrey V. Grant, Parisa Adimi, Nahal Mansour...

The Journal of Clinical Investigation online: August 1, 2012

The Journal of Clinical Investigation online: August 1, 2012 Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections Amandine Crequer, Anja Troeger, Etienne Patin, Cindy S. Ma, Capucine Picard, Vincent Pedergnana, Claire Fieschi, Annick Lim, Avinash Abhyankar, Laure Gi...

Molecular Cell online: July 26, 2012

Molecular Cell online: July 26, 2012 DNA methylation dynamics during in vivo differentiation of blood and skin stem cells Christoph Bock, Isabel Beerman, Wen-Hui Lien, Zachary D. Smith, Hongcang Gu, Patrick Boyle, Andreas Gnirke, Elaine Fuchs, Derrick J. Rossi and Alexander Meissner

Starr collaboration illuminates mysterious pathway to immortality in cancer cells

Cancer cells are immortal because they circumvent failsafe mechanisms that stop out-of-control cell proliferation. One of these mechanisms – the progressive shortening of chromosomes – is prevented by replenishment of telomeres, the protective elements at the ends of chromosomes. Most cancer cel...

Journal of Experimental Medicine 209: 1469-1479 (July 23, 2012)

Journal of Experimental Medicine 209: 1469-1479 Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein Florian Klein, Christian Gaebler, Hugo Mouquet, D. Noah Sather, Clara Lehmann, Johannes F. Scheid, Za...

Jeffrey Ravetch wins 2012 Sanofi – Institut Pasteur Award

Jeffrey V. Ravetch, head of the Leonard Wagner Laboratory of Molecular Genetics and Immunology at Rockefeller University, has been given the 2012 Sanofi – Institut Pasteur Award for discovering mechanisms by which antibodies carry out their diverse biological functions. He is one of four scientis...