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Scientists show how a neuron gets its shape

Ask a simple question, get a simple answer: When Abraham Lincoln was asked how long a man’s legs should be, he absurdly replied, “Long enough to reach the ground.” Now, by using a new microscopy technique to watch the growth of individual neurons in the microscopic roundworm Caenorhabditis el...

Sean Brady named HHMI Early Career Scientist

Sean F. Brady, assistant professor and head of the Laboratory of Genetically Encoded Small Molecules at The Rockefeller University, has been named a Howard Hughes Medical Institute (HHMI) Early Career Scientist. The Early Career Scientist program, launched in 2008, was created to support the work...

Rockefeller neuroscientist applies basic science to health care reform

A self-described “molecular sociologist” is extending his basic research to the national policy debate on health care reform. Bruce McEwen, head of the Laboratory of Neuroendocrinology, led a panel of scientific experts last month at the Institute of Medicine’s Summit on Integrative Medicine a...

Epigenetic mark guides stem cells toward their destiny

Not all stem cells are completely blank slates. Some, known as adult stem cells, have already partially embraced their fates and are capable of becoming only cells of a particular type of tissue. So how do these tissue-specific stem cells restrict their fate? In research to appear in the March 20...

Research defines dendritic cell lineage

Dendritic cells were discovered more than 30 years ago, but their pedigree has never been fully charted. They were known to be key immune system cells born in bone marrow, but their adolescence remained a mystery, their path to infection-fighting adulthood confused. Now, in experiments published ...

Rockefeller receives new $4.8 million state grant to fund stem cell research

Rockefeller University, which has New York state’s oldest research program devoted to understanding the biology of human embryonic stem cells, will receive $4.8 million from the state to establish new facilities for studying the molecular basis of how stem cells are maintained and how they differ...

A natural approach for HIV vaccine

For 25 years, researchers have tried and failed to develop an HIV vaccine that will generate antibodies to kill the virus before it takes hold. Only four “super antibodies” have been discovered that might do the job, but they have proved impossible to induce in people so far. Now, in research pu...

Scientists discover master regulator of motor neuron firing

When the Human Genome Project was complete, DNA bowed out of the limelight and gave way to RNA as a major player in genetic regulation. Now, findings at Rockefeller University mirror this ideological shift, revealing that one of the most important physiological events in the body — the wiring of ...

2008 Pearl Meister Greengard Prize awarded to three leading biologists

The Rockefeller University has announced the winners of the fifth annual Pearl Meister Greengard Prize: Elizabeth H. Blackburn of the University of California, San Francisco; Carol W. Greider of The Johns Hopkins University School of Medicine; and Vicki Lundblad of the Salk Institute for Biologic...

Measuring the strength needed to move chromosomes

It’s about as long as the width of a human hair and only half that length across. So it’s tiny — measured in millionths of a meter — and extremely tricky to manipulate. But the meiotic spindle plays so irresistibly important a role in separating our chromosomes during cell division that scie...