Skip to main content

Protein linked to antibodies also has an antiviral function, researchers show

In biology, it’s actually possible to teach an old dog a new trick. A new finding from Rockefeller University’s Nina Papavasiliou has shown that a protein called AID, which is involved in creating diversity among immune system antibodies, evolved long before antibodies themselves did — suggest...

Structural analysis of SpvB protein show how Salmonella bacteria hijack a cell

When Salmonella bacteria attack, they create their own compartment or vacuole in the host’s cell, in which they replicate. Now, in a cover article published this week in the journal Structure, Rockefeller University scientists show how the pathogen uses a protein called SpvB to create this comp...

Leprosy bacteria lead to new understanding of nerve damage and cell proliferation

For nervous system cells, specialization is a one-way street. But as is often the case in biology, the rules have exceptions. Glial cells — nervous system cells that form a highly specialized insulating sheath called myelin that surrounds nerve fibers — under certain conditions can “de-differe...

Expression of 'Blimp1' gene leads to the discovery of cells responsible for skin's sebaceous gland

Mice may not get zits, but they do have oily skin. This week, new research on mice from Rockefeller University shows how the cells responsible for oil production develop, and uncovers clues about how stem cells renew and differentiate. The research focuses on the skin’s sebaceous gland, which i...

Rockefeller researchers receive Gates Foundation grant for HIV vaccine research

The Bill & Melinda Gates Foundation has announced 16 grants totaling $287 million to create an international network of highly collaborative research consortia focused on accelerating the pace of HIV vaccine development. The grants will support a range of innovative approaches for designing an ef...

Scientists ID a single sugar that allows antibodies to fight inflammation

For years, researchers have struggled to understand how IVIG works. Its ability to treat autoimmune diseases seemed to be an apparent contradiction. Intravenous immunoglobulin (IVIG) is a complex mixture of IgG antibodies made from human plasma that contains the pooled antibodies from thousands o...

Evidence of rapid evolution is found at the tips of chromosomes

In terms of their telomeres, mice are more complicated than humans. That’s the finding from a recent Rockefeller University study, which shows that mice have two proteins working together to do the job of a single protein in human cells. The findings, published recently in Cell, suggest that the ...

Nine Rockefeller labs to receive Stem Cell Initiative grants

The Tri-Institutional Stem Cell Initiative, comprising three leading New York City biomedical research institutions — Memorial Sloan-Kettering Cancer Center, The Rockefeller University and Weill Medical College of Cornell University — has announced the first wave of stem cell research projects t...

Twenty-eight degrees awarded at Rockefeller's 48th convocation

Rockefeller University’s 48th Convocation, held yesterday, marked the completion of graduate studies for 28 students. Twenty-six of this year’s 28 graduates participated in a formal presentation of Ph.D.s held in Caspary Auditorium on the university’s Manhattan campus. President Paul Nurse a...

Human stem cells can contribute to a developing mouse embryo, despite evolutionary differences

Using a newly derived line of human embryonic stem cells, Rockefeller University researchers have coaxed human cells to grow in mouse tissue. Ali Brivanlou, an embryologist who specializes in studying how the nervous system develops, and his colleagues demonstrated that despite the evolutionary d...