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"Outlaw" organism turns informant

African trypanosome source of scientific insight In a critical scene in the film remake of the classic 1960s TV series "The Fugitive," actor Harrison Ford sheds his coat and replaces it with another. This simple deception allows him to escape detection by the swarm of police officers trailing him...

Noise inner life cells

Process of "reading" genes not perfectly predictable Within the smoothly operating factory that is the cell, tiny molecular machines carry out their tasks with order and certainty. Or at least that's what many scientists once believed. In a recent issue of Science, researchers at The Rockefeller ...

Wrong Proteins Targeted in Battle Against Cancer?

Lasker recipient James E. Darnell contends drug developers should focus more on "transcription factor" proteins Researchers may be looking for novel cancer drugs in the wrong places, says Rockefeller University Professor James E. Darnell Jr., M.D., in an article in this month's Nature Reviews Ca...

"CAF" protein mystery solved by AIDS researchers

Blood proteins shown to thwart HIV provide clues to potential new treatment Acclaimed AIDS researcher David Ho, M.D., a Rockefeller University Irene Diamond Professor who heads the Aaron Diamond AIDS Research Center (ADARC), and his research team, have discovered that several natural proteins -a...

Lasker Award Honors Rockefeller University's James Darnell

"Special Achievement in Medical Science" recognizes a groundbreaking researcher, influential writer and mentor James E. Darnell Jr., M.D., the pioneering researcher in the field of gene regulation — who has nurtured the careers of over 100 young, talented scientists — was honored today with the...

One gene, two important proteins

Researchers discover gene variation in cancer-causing "STAT" family encodes two —not one—functional proteins When the Human Genome Project first revealed last year that humans possess only an estimated 30,000 genes — fives times more than a mustard weed plant — the fact that many of our g...

Rockefeller researchers provide the first functional evidence for mammalian pheromone receptors

Pheromones — chemical signals that influence social and reproductive behaviors — have been studied since the 1950s, but the molecules in the mammalian nervous system that actually detect pheromones have remained elusive. Now, a team of researchers, led by The Rockefeller University's Peter Momb...

Dinosaur ancestor's vision possibly nocturnal

Researchers recreate 240-million year old protein in test tube Call it "Triassic Park": with statistics, instead of amber-preserved DNA, researchers at the Howard Hughes Medical Institute at The Rockefeller University and Yale University recreated in the test tube a functional pigment that would ...

Natural-born killers enlisted to fight anthrax

Phage enzymes may offer powerful novel method to wipe out anthrax bacteria in seconds Researchers at The Rockefeller University have hit upon a promising method for rapidly and effectively treating people infected with the deadly anthrax bacterium — including feared drug-resistant strains. The ...

Pivotal Brain Processor Decreased in Schizophrenia

Lower Levels Could Explain Disruption in Mental Function; Study Points Toward Better Treatments New York, NY (August 14, 2002) -- Levels of a pivotal signal processor in the brain are reduced significantly in people with schizophrenia, a study by scientists at The Rockefeller University, Weill Co...