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Displaying 95 of 2916 articles.
Llamas immune to coronavirus, what zebrafish are thinking, and other memorable science stories of 2020 
...Shortly thereafter, Jean-Laurent Casanova and colleagues made headlines with two reports revealing that people with the most severe cases of the disease frequently lack interferon I, a cluster of proteins that repel viruses, providing the first molecular explanation for why some ...
Researchers uncover molecular mechanisms of rare skin disease
...Led by Rockefeller scientist Jean-Laurent Casanova, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases, a group of researchers recently elucidated the molecular mechanisms that make people with EV vulnerable to ß-HPVs. In a new study, published in the Journ...
Study pinpoints rare genetic change that may boost risk of HPV-related illness
...We’ve cracked the enigma of why the boys developed these warts,” says lead investigator Jean-Laurent Casanova, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases. The findings add to a growing body of evidence that is changing how researchers think about in...
Genetic mutation identified as culprit in rare infectious disease
...In an article published in eLife, Jean-Laurent Casanova has uncovered the human genetics factors that make these outliers susceptible to infection. His team suspected that Whipple’s is the latest in a growing number of genetic defects that increases people’s vulnerability to spec...
Milestones
...Jean-Laurent Casanova, the 2011 InBev-Baillet Latour Health Prize, Beligum’s highest scientific honor. With a value of 250,000 euros, the InBev-Baillet prize recognizes the practical application of basic research; Dr. Casanova is honored for his work on the identification ...
Awards, arrivals, and promotions
Congratulations to our latest award winners: Jean-Laurent Casanova has been recognized with the Stanley J. Korsmeyer Award for his work investigating the genetic basis of pediatric infectious diseases. The award is given by the American Society for Clinical Investigation, an honor s...
Rockefeller hosts the first New York City symposium on human genetics
...Spearheaded by Rockefeller professor Jean-Laurent Casanova, who is working closely with physician-scientist Bruce Gelb at Icahn School of Medicine at Mount Sinai and geneticist David Goldstein at Columbia University, the group plans to organize two meetings annually. “The goal is...
Study identifies genetic mutation responsible for tuberculosis vulnerability
...Hoping to better understand why only some people are prone to TB, Jean-Laurent Casanova worked with clinicians across the world to collect DNA samples from patients with active forms of the disease. By analyzing these samples, the researchers discovered that the risk of developin...
Researchers develop gene-filtering tool to identify disease-causing mutations
...A new tool, developed by scientists in Jean-Laurent Casanova’s St. Giles Laboratory of Human Genetics of Infectious Diseases at Rockefeller University aims to predict whether a given human gene is likely to harbor disease-causing mutations. The hope is that their tool, described ...
New research explains why a common bacterium can produce severe illness
...Jean-Laurent Casanova, head of St. Giles Laboratory of Human Genetics of Infectious Diseases and Howard Hughes Medical Institute Investigator, led a team of researchers to uncover how two different conditions—a genetic immunodeficiency and delayed acquired immunity—can combine to...
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