...Jean-LaurentCasanova, head of the Laboratory of Human Genetics of Infectious Diseases, and colleagues examined the genomes of 17 people who had deep dermatophytosis but were otherwise healthy — their immune systems were working well and should have been able to fight off infecti...
...Years after her ordeal, which she survived, scientists led by Jean-LaurentCasanova discovered that it could be explained by a rare mutation she carries that prevented her from producing a protein, interferon, that helps fight off the virus. “This is the first example of a common...
...Giles lab, headed by Jean-LaurentCasanova, set out to identify the gene responsible for isolated congenital asplenia. He and his colleagues conducted an international search for patients, and identified 38 affected individuals from 23 families in North and South America, Europe ...
Pollard, Catherine Gaud, Pierre Frange, Daniel Orbach, Jean-Francois Emile, Jean-Louis Stephan, Ricardo Sorensen, Alessandro Plebani, Lennart Hammarstrom, Mary Ellen Conley, Licia Selleri and Jean-LaurentCasanova
Proceedings of the National Academy of Sciences USA online: March 18, 2013 The human gene connectome as a map of short cuts for morbid allele discovery Yuval Itana, Shen-Ying Zhang, Guillaume Vogt, Avinash Abhyankar, Melina Herman, Patrick Nitschke, Dror Fried, Lluis Quintana-Murci, Laurent Abel ...