New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations.
New study demonstrates how high-affinity B cells "bank" their best traits instead of rolling the dice and risking deleterious mutations, with implications for better vaccine design.
Mei, a graduate student in Sohail Tavazoie’s lab, is being honored for work showing that a commonly inherited mutation governs breast cancer metastasis and influences survival.
Most obese patients grow resistant to satiety signals from the hormone leptin. A new study shows that leptin sensitivity can be restored in mice, leading to weight loss.
A collaboration between Rockefeller, MSK, and Weill Cornell answers a longstanding
mystery about the basic biology of the hepatitis B virus, while also proposing a novel therapy.